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Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
Madeca Cream - Time Reverse & PDRN Duo
4.8 | 748 reviews

Madeca Cream - Time Reverse & PDRN Duo

$39.99$64.99

PDRN rebuilds underneath, Time Reverse firms the top. Sixty seconds a night.

SEE BENEFITS
PDRN CREAM

Purified salmon DNA. Korean clinics put it on the second a laser finishes, because it tells skin to rebuild instead of slowly closing over. It's the one layer your moisturizer has never reached, and it's where the slackness starts.

TIME REVERSE

30,000ppm TECA with retinol, collagen, elastin and hyaluronic acid. Lines sit shallower. Tone evens out. Press your cheek and it springs back instead of holding the dent.

THE DUO

Aging is two problems wearing one face. Use one cream and you plateau, because the half you're not treating is the half that's dragging. Use both and the change shows up in your profile, not just your glow.

Which cream
How many

Renews automatically every 30 days at $39.99 until you cancel. Skip, pause or cancel any time in your account. No fee to cancel.

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See it in action

Over 124M Views On TikTok
Expert Approved

Powered by PDRN and Centella Asiatica, Expert Barrier Cream is formulated to visibly calm irritation, restore the skin barrier, and deliver deep lasting hydration, results you can see and feel.

Dr. Ji-Yoon LeeDermatology & Skincare Specialist

The protocol

Two Korean creams that work in order.

Expert Madeca Cream Active Renew PDRN goes on first. It calms the skin and repairs the barrier.

Madeca Cream Time Reverse goes over the top. 30,000ppm TECA and retinol firm and smooth.

One repairs, one rebuilds. That is why they are sold as a pair.

Why two steps

Firming ingredients need a healthy barrier to work. If yours is stressed from retinol, sun or just time, they sit on the surface and do very little.

PDRN settles and repairs first, so the TECA and retinol in Time Reverse have something to work on.

Who it's for

Fine lines and wrinkles. Firmness slipping around the jaw and neck. Dry, tight or reactive skin. Dullness and uneven tone. Skin that has been through too many actives.

If your skin is very sensitive, patch test Time Reverse first because it contains retinol.

How to use

Last step of your evening routine, on clean skin.

PDRN first. Spread evenly, pat until absorbed. Then Time Reverse over the top, same way. About sixty seconds for both.

Retinol at night only. Wear SPF the next morning.

Ingredients

Expert Madeca Cream Active Renew PDRN. Sodium DNA (PDRN), 7 type hyaluronic acid complex, Centella TECA, Ceramide NP, Phytosphingosine, Niacinamide, Panthenol, Adenosine.

Madeca Cream Time Reverse. TECA complex, Retinol, Ceramide NP, Sodium DNA, multi form hyaluronic acid, Ectoin, Resveratrol, Niacinamide, Centella Asiatica protein extract.

Both 50ml.

FAQ

Which one do I need?
Both creams is the protocol and what almost everyone buys. The singles are there if you already own one.

How long before I see anything?
Hydration and calm come first, usually within the first week. Firmness and tone take longer because retinol works on cell turnover. Four to eight weeks is where lines and spots start to shift.

Can I use it with my other products?
Yes. Use them as the last step at night, after serums. Skip other retinol products on the same night.

Marie P.★★★★★

I started using both creams 8 weeks ago, PDRN in the morning, Time Reverse at night. The lines around my eyes are visibly softer, my skin feels firmer, and last week my coworker asked if I changed something. I hadn't, except my entire routine. At 38, I finally feel like my skin is working with me again.

4.8748 Reviews

REAL RESULTS, REAL SKIN

Everything else in anti aging asks you to wait. This one doesn't. You get the first change overnight, and it builds from there.

Marie, 37
Marie, 37
Week 1Week 4

I finally found something that works for my sensitive skin

“I've tried so many creams but they always broke me out or caused redness. This is the first one that actually calmed my skin down. After two weeks my acne marks are visibly fading and my skin feels so balanced”

Marie, 37
Brenda, 43
Brenda, 43
Week 1Week 4

My skin finally caught up with how I feel inside.

“8 weeks in and the fine lines around my mouth are noticeably softer. My skin looks firmer, more lifted. I wasn't expecting much, I'd been disappointed before. This one surprised me.”

Brenda, 43
91%

of users noticed firmer, smoother skin within the first two weeks

Emma, 52
Emma, 52
Week 1Week 3

I cancelled my Botox appointment

“Three months with this cream and I genuinely don't need it. The forehead lines I've had for years have softened significantly. My daughter noticed before I did. I'm not going back to anything else.”

Emma, 52
Sydney, 47
Sydney, 47
Week 1Week 4

The first cream that actually does what it says

“I was skeptical. I've tried everything. But by week four my skin felt different... firmer, smoother, more alive. The crow's feet I'd accepted as permanent are fading. At 47, I didn't think that was still possible.”

Sydney, 47
89%

of users noticed calmer, more hydrated skin within the first week

Dana, 29
Dana, 29
Week 1Week 3

My skin barrier is finally healing

“I damaged my skin barrier from over-exfoliating. This cream brought it back to life. The redness is gone, my skin feels plump and healthy again. I genuinely can't imagine my routine without it now”

Dana, 29
Rachel, 32
Rachel, 32
Week 1Week 4

Worth every single penny

“I was skeptical about PDRN but after 4 weeks my skin looks younger and smoother than it has in years. My fine lines around my mouth are noticeably softer. My friends keep asking what I'm doing differently.”

Rachel, 32
Korean skincare, done properly

sixty seconds a night

Two creams, last thing at night, nothing to rinse off. Short on purpose, because a routine you skip does nothing.

The routine

pdrn first. time reverse over the top.

Sixty seconds, last step, every evening.

  1. 1

    Cleanse

    Clean skin, nothing else on it yet. This is the last step of your evening routine, not the first.

  2. 2

    PDRN first

    Pea sized, face and neck, pat it in. This one's doing the work you can't feel happening.

  3. 3

    Time Reverse over the top

    Same amount, straight over the top. Retinol and TECA go after the lines and the firmness, and seal the first layer in underneath.

  4. 4

    Go to bed

    Done. Nothing to wash off. It works while you sleep.

what changes, and when

The redness stops
Week 1

The redness stops

The patches that come and go stop coming back. Your face stops stinging when you wash it. TECA at 30,000ppm moves fast on this.

People start asking
Week 8

People start asking

The dark spots from last summer have gone. Lines sit shallower. Nobody can name what's different, only that something is.

The formula

why one cream was never enough

Your moisturizer reaches the top layer of your skin. Sagging doesn't start there. It starts underneath, where skin stops regenerating at the rate it used to, and nothing sitting on the surface can reach that, whatever it costs.

Expert Madeca Cream PDRN

Sodium DNA renews at the cellular level. Centella TECA and Ceramide NP rebuild the barrier. A 7 type hyaluronic acid complex holds the water in.

This is the layer that fixes damage.

Goes on
First, on clean skin
Best for
Barrier damage and dullness
Works on
Repair and renewal
Us
50ml
  • Renews at the cellular level
  • Rebuilds the skin barrier
  • Calms redness and sensitivity
  • 7 type hyaluronic acid complex

Apply first, before Time Reverse.

what it’s not

Not a ten step routine

Two creams, sixty seconds, once a day.

Not a serum you rinse

Leave on overnight. Nothing to wash out.

Not a five year old formula

PDRN and the TECA complex are why this line exists.

Not a mystery brand

Centellian 24, by Dongkook Pharmaceutical, since 1968.

Straight comparison

against what you’re using now

Most anti aging routines do one job well and leave the other one open.

Madeca Protocol
A single retinol serum
A rich night cream
Repairs the barrier
Works on fine lines
PDRN at the root
Calms redness
Fades dark spots
Under a minute
Under 45c a day
Always Sometimes Rarely

A single retinol serum means a treatment step with no barrier support. A rich night cream means moisture with no active turnover.

WHAT PEOPLE SAY

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  1. 5 0
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0% would recommend this product

0 reviews
  • Emma
    17 September 2026

    smooth

    this product has a really nice smell.. and it is so moisturising.. makes the skin feel soft and glowy.. works well under makeup.. I apply it day and night

  • Pilar
    17 September 2026

    EXCELENTE

    “Muy buen producto. Llegó en buen estado, cumple lo que promete y se adapta bien a mi piel. Lo he usado varios días y estoy satisfecha con los resultados.”

  • opal
    16 September 2026

    anti-aging cream

    i gave it to my mum and she says its really good, love it, might repurchase again

  • Javier
    16 September 2026

    madeca cream

    -súper hidratante -textura pesada -uso para la noche -recomendada para pieles maduras -sin fragancia

  • Pilar
    16 September 2026

    Me gusta

    La consistencia es sólida, llevo algunos días aplicándola sin ninguna realización todo bien mi piel amanece muy suave

  • Penelope
    15 September 2026

    “Calm and Nourishment in One Step”

    The texture is rich and slightly thick, so I mostly use it at night. It contains Centella Asiatica extract (TECA), niacinamide, and panthenol, which really help calm the skin, reduce redness, and leave a healthy, glowing finish. After just a few days, my skin felt softer and less tight.

  • DESHAWN B.
    15 September 2026

    best product ever!

    my skin has been extra soft, clean, and glowing! I put it on after cleansing and toner during night, and when I wake up after cleansing and toner… I’ve gotten so many questions how to keep my skin glowing :)

  • AALIYAH T.
    14 September 2026

    Amazing moisturizer

    Perfect for mature skin. Super lightweight and hydrating. Definitely recommended!

questions

Why not just buy one?

You can, and plenty of people start there. But the red cream on its own plateaus, because the slackness is coming from a layer it can't reach. And PDRN on its own doesn't touch the lines on the surface.

One cream gets you half. Both gets you the jawline. In Korea they're sold side by side for exactly this reason.

Can I use it with retinol I already have?

Time Reverse already contains retinol. Stacking another on top is how people end up irritated. Use this instead of your current retinol, not alongside it.

Morning or night?

Night. Retinol breaks down in sunlight and makes skin more sensitive to it, so it belongs in the evening routine and SPF belongs in the morning one.

Sensitive skin?

Start three nights a week and build up. Centella, Ceramide NP and Panthenol are in there precisely because retinol needs the barrier supported while it works.

If it stings, drop to PDRN only for a two weeks and reintroduce Time Reverse after.

What’s PDRN?

Polydeoxyribonucleotide. It appears on the ingredient list as Sodium DNA. It came out of wound care and moved into skincare because of what it does for repair and renewal.

How long does one pack last?

Two 50ml creams, used once a night, is roughly two months.

Three packs plus one free is eight months, which is why it's the one most people take.

Is it tested on animals?

Korean cosmetics have been free of mandatory animal testing since 2018.

Will it work under makeup?

It's a night routine, so the question doesn't usually come up. If you do use it in the day, skip Time Reverse and wear SPF.

Pregnant or breastfeeding?

Retinol is one of the ingredients doctors usually ask you to pause. Ask yours before starting, or use PDRN on its own in the meantime.

How do I store it?

Cool, dry, out of direct sunlight. No fridge needed. Close it properly, retinol doesn't like air.

Delivery and returns

Free delivery on every order, dispatched same day if you order before 3pm.

Thirty days. If nothing's changed, email us and we'll refund you.

The legal bit

Cosmetic product. Not intended to diagnose, treat, cure or prevent any disease. Individual results vary.